From 1981 to 1987 I studied biochemistry at the Institut für Biochemie of the Freie Universität Berlin. Studying the regulation of protein kinase C for my diploma thesis, I stayed after graduation in Prof. Ferdinand Hucho's neurochemistry group to work on my Ph.D. thesis focussing on protein kinase C and GTP-binding proteins in cellular signal transduction. I investigated the role of these proteins in signalling toward the cell nucleus. After defending my thesis in 1992, I moved to Prof. Dr. Reinhard Jahn's research group at the Yale Medical School in New Haven, Connecticut, investigating the interaction of SNARE proteins in neurotransmitter release from the presynaptic nerve terminal. End of 1996 I returned to Germany and the Freie Universität Berlin and joined again Prof. Hucho's group. I acted as substituting lecturer taking on the teaching responsibilities of Prof. Hucho, when he retired in autumn 2005.
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Since my return to the Freie Universität, I am working on the identification of nuclear envelope proteins (nuclear envelope proteomics), the characterization of inner-nuclear-membrane proteins, of LUMA in particular, and on aspects of signalling at the nuclear envelope, particularly through serine/threonine- and tyrosine-phosphorylation. Research at the Freie Universtät Berlin came always with teaching assignments, which thaught me to teach "molecular bioscience" at all levels, which recently gave me the opportunity to teach also at the Staatliche Technikerschule Berlin and in the B.Sc.(hons) program for clinical research, a program of the PAREXEL Akademie and the University of Wales.
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