"Functional Organization of the Nuclear Envelope in Health and Disease", Berlin, October 7 - 9, 2004

Programme
 







Thursday, October 7






9:00 am - 2:00 pm
Registration at the Zuse Institute Berlin



2:30 am - 3:00 pm
Opening Remarks



3:00 pm - 6:00 pm
Nuclear-Envelope Dynamics



     Jan Ellenberg
Systematic analysis of nuclear pore complex dynamics in interphase and M-phase of live mammalian cells



     Ueli Aebi
Structural dissection of nucleocytoplasmic transport



     Philippe Collas
Role of AKAP149 - PP1 interaction in nuclear envelope dynamics



     Reimer Stick

Function of B-type lamins in early development of Xenopus


6:30 pm - 10:00 pm
Poster and Cheese









Friday, October 8







9:00 am - 12:00
Novel Nuclear-Envelope Proteins



     Henning Otto
On target: identification of nuclear-envelope membrane proteins



     Eric Schirmer
Fishing for NETs (Nuclear Envelope Transmembrane proteins) with subtractive proteomics



     Janet Cronshaw
ALADIN: a link between nuclear transport and human disease



     Angelika Noegel

NUANCE and Enaptin, two giant proteins at the nuclear envelope


12:00 - 1:30 pm
Lunch Break



1:30 pm - 3:30 pm
Poster Session



3:30 pm - 6:30 pm
Structures and Functions of Nuclear-Envelope Proteins



     Harald Herrmann
Experimentally generated mutations of lamina proteins effecting nuclear envelope architecture



     Amos Simon
Repression of transcription at the nuclear envelope - LAP2beta/HDAC3 complex induces deacetylation of histone H4



     Glenn Morris
Functions of the emerin-lamin A/C complex: what can we learn from muscular dystrophy



     Malini Mansharamani

Nuclear membrane protein MAN1: direct binding to emerin and two modes of binding to BAF via the LEM-domain and a proposed SRV motif


7:30 pm -
Banquet








Saturday, October 9







9:00 am - 12:40
The Nuclear Envelope in Disease



     Manfred Wehnert
Pleiotropic disease phenotypes of LMNA mutations in man



     Gisèle Bonne
Clinical, genetic and functional heterogeneity in laminopathies



     Brigitte Buendia
Analysis of the cellular mechanisms of laminopathies in patient and mouse cell lines



     Thorsten Marquardt




     Katrin Hoffmann

Phenotypic and functional variance in lamin B receptor-associated dieseases


12:40 - 1:10 pm
Closing ceremony

 

Last update: 14.9.2004, Henning Otto