Publications

44. V. Böhrsch, T. Mathew, M. Zieringer, M.R.J. Vallée, L.M. Artner, J. Dernedde, R. Haag, C.P.R. Hackenberger
Org. Biomol. Chem. 2012, DOI: 10.1039/C2OB25207D
Chemoselective Staudinger-Phosphite Reaction of Symmetrical Glycosyl-Phosphites with Azido-Peptides and Polygycerols
(10-year-anniversairy issue of Org. Biomol. Chem.)
 
43. H. Möller, V. Böhrsch, J. Bentrop, J. Bender. S. Hinderlich, C.P.R. Hackenberger
Angew. Chem. 2012, DOI:10.1002/ange.201108809
Angew. Chem. Int. Ed. 2012, DOI:10.1002/anie.201108809
Glycan-Specific Metabolic Oligosaccharide Engineering of C7-Substituted Sialic Acids
 
 
42. M. Broncel, E. Krause, D. Schwarzer, C.P.R. Hackenberger
Chem. Eur. J. 2012, 18, 2488-2492
The Alzheimer's disease-related tau protein as a new target for chemical protein engineering (selected as VIP-paper)
 
41. L.M. Artner, L. Merkel, N. Bohlke, F. Beceren-Braun, C. Weise, J. Dernedde, N. Budisa, C.P.R. Hackenberger
Chem. Commun. 2012, 48, 522-524
Site-selective modification of proteins for the synthesis of structurally defined multivalent scaffolds
 
40. M.R.J. Vallée, P. Majkut, I. Wilkening, C. Weise, G. Müller, C.P.R. Hackenberger
Org. Lett. 2011, 13, 5440-5443
Staudinger-Phosphonite Reactions for the Chemoselective Transformation of Azido-Containing Peptides and Proteins
 
39. I. Wilkening, G. del Signore, W. Ahlbrecht, C.P.R. Hackenberger
Synthesis 2011, 17, 2709-2720
Lewis acid or alkyl halide promoted rearrangements of phosphor- and phosphinimidates to N,N-disubstituted phosphor- and phosphinamidates (Feature Article)
  TOC
38. H. Möller, V. Böhrsch, C.P.R. Hackenberger, S. Hinderlich
J. Carb. Chem. 2011, 4-6, 334-346
N-azidoacetylomannosamine and N-azidoacetylgalactosamine incorporation into N-glycans of recombinantly expressed human lactotransferrin by metabolic oligosaccharide engineering
37. H. Möller, V. Böhrsch, L. Lucka, C.P.R. Hackenberger, S. Hinderlich
Mol. Biosyst. 2011, 7, 2245-2251
Efficient metabolic oligosaccharide engineering of glycoproteins by UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE) knock-down
36. P. Majkut, V. Böhrsch, R. Serwa, M. Gerrits, C.P.R. Hackenberger
in "Methods in Molecular Biology, Vol. 794: Unnatural Amino Acids", Springer, Loredano Pollegioni, Stefano Servi (eds), 2011 in press
Site specific modification of proteins by the Staudinger-phosphite reaction (Book chapter)
35. C. Smet-Nocca, M. Broncel, J.-M. Wieruszeski, C. Tokarski, X. Hanoulle, A. Leroy, I. Landieu, C. Rolando, G. Lippens, C.P.R. Hackenberger
Mol. Biosyst. 2011, 7, 1420-1429
Identification of O-GlcNAc sites within peptides of the Tau protein and their impact on phosphorylation
  TOC
34. I. Wilkening, G. del Signore, C.P.R. Hackenberger
Chem. Commun. 2011, 47, 349-351
Synthesis of phosphonamidate peptides by Staudinger reactions of silylated phosphinic acids and esters Emerging Investigator Issue
  TOC
33. M.M. Chen, A.I. Bartlett, P.S. Nerenberg, C.T. Friel, C.P.R. Hackenberger, C.M. Stultz, S.E. Radford, B. Imperiali
Proc. Natl. Acad. Sci. 2010, 107, 22528-22533
Perturbing the folding energy landscape of the bacterial immunity protein Im7 by site-specific N-linked glycosylation
32. R. Serwa, B. Horstmann, P. Majkut, J.-M. Swiecicki, M. Gerrits, E. Krause, C.P.R. Hackenberger
Chemical Science 2010, 1, 596-602
Site-Specific PEGylation of Proteins by a Staudinger-Phosphite Reaction
  TOC
31. M. Mühlberg, D. Jaradat, R. Kleineweischede, I. Papp, D. Dechtrirat, S. Muth, M. Broncel, C.P.R. Hackenberger
Bioorg. Med. Chem. 2010, 18, 3679-3686
Acidic and Basic Deprotection Strategies of Borane-protected Phosphinothioesters for the Traceless Staudinger Ligation
  TOC
30. R. Serwa, J.-M. Swiecicki, D. Homann, C. P. R. Hackenberger
J. Pep. Sci. 2010, 16, 563-567
Phosphoramidate-Peptide Synthesis by Solution and Solid-Phase Staudinger-Phosphite Reactions
  TOC
29. D. M. M. Jaradat, H. Hamouda, C. P. R. Hackenberger
Eur. J. Org. Chem. 2010, 26, 5004-5009
Solid-phase synthesis of phosphoramidate-linked glycopeptides
  TOC
28. M. Broncel, S. C. Wagner, K. Paul, C. P. R. Hackenberger, B. Koksch
Chem. Commun. 2010, 46, 3080-3082
Enzymatically triggered amyloid formation: an approach for studying peptide aggregation
  TOC
27. M. Broncel, J. A. Falenski, S. C. Wagner, C. P. R. Hackenberger,
B. Koksch
Chem. Eur. J. 2010, 16, 7881-7888
How Post-translational Modifications Influence Amyloid Formation: A Systematic Study of Phosphorylation and Glycosylation in Model Peptides
  TOC
26. M. Broncel, S. C. Wagner, K. Paul, C. P. R. Hackenberger, B. Koksch
Org. Biomol. Chem. 2010, 8, 2575-2579
Towards understanding secondary structure transitions: phosphorylation and metal coordination in model peptides
  TOC
25. V. Böhrsch, R. Serwa, P. Majkut, E. Krause, C. P. R. Hackenberger Chem. Commun. 2010, 46, 3176-3178
Site-specific Functionalisation of Proteins by a Staudinger-type reaction using unsymmetrical phosphites
  TOC
24. C. P. R. Hackenberger, J. W. Bode, D. Schwarzer
in "Amino Acids, Peptides and Proteins in Organic Chemistry", Wiley-VCh, Andrew B. Huges (ed.), 2010, 445-494
Chemoselective Peptide Ligation - A Privileged Tool for Protein Synthesis (Book Chapter)
23. A.K. Udit, C. P. R. Hackenberger, Mary K. O'Reilly
ChemBioChem 2010, 11, 481-484
Chemically tailored multivalent virus platforms - from drug delivery to catalysis (Highlight)
  TOC
22. V. Böhrsch, C. P. R. Hackenberger
ChemCatChem 2010, 2, 243-245
Suzuki-Miyaura couplings on proteins - a simple and ready to use catalytic system in water (Highlight)
  TOC
21. C. P. R. Hackenberger, H.-D. Arndt, D. Schwarzer
Chemie in unserer Zeit 2010, 44, 198-206
Semisynthese: Ein zentrales Werkzeug für die Chemische Biologie (Review)
20. H.-D. Arndt, C. P. R. Hackenberger, D. Schwarzer
Chemie in unserer Zeit 2010, 44, 130-137
Semisynthese: Chemie mit den Molekülen der Natur (Review)
19. R. Serwa, I. Wilkening, G. del Signore, M. Mühlberg, I. Claußnitzer, C. Weise, M. Gerrits, C. P. R. Hackenberger
Angew. Chem. 2009, 121, 8382-8387
Angew. Chem. Int. Ed. 2009, 47, 8234-8239
Chemoselective Staudinger-Phoshpite Reaction of Azides for the Phosphorylation of Proteins
  TOC
18. C. P. R. Hackenberger, D. Schwarzer
Angew. Chem. 2008, 120, 10182-10228
Angew. Chem. Int. Ed. 2008, 47, 10030-10074
Chemoselective Ligation and Modification Strategies of Peptides and Proteins
  TOC
17. I. Wilkening, G. del Signore, C. P. R. Hackenberger
Chem. Commun. 2008, 2932-2934
Synthesis of N,N-disubstituted phosphoramidates via
a Lewis acid-catalyzed phosphorimidate rearrangement
  TOC
16. R. Kleineweischede, C. P. R. Hackenberger
Angew. Chem. 2008, 120, 6073-6078 
Angew. Chem. Int. Ed. 2008, 47, 5984-5988
Chemoselective Peptide Cyclization by Traceless Staudinger
Ligation
  TOC
15. C. P. R. Hackenberger, S. Hinderlich
ChemBioChem. 2007, 8, 1763-1765
Chemoselective Labeling of Engineered Fucosylated Glycoproteins
14. C. P. R. Hackenberger
ChemBioChem. 2007, 8, 1221-1223
A Synthetic Kiss of Death: Expressed protein Ligation of a Ubiquitin-Peptide Conjugate
13. C. P. R. Hackenberger
Org. Biomol. Chem. 2006, 4, 2291-2295
The Reduction of Oxidized Methionine Residues in Peptide Thioesters with NH4I/Me2S
12. C. P. R. Hackenberger,
Chemie in unserer Zeit (ChiuZ), 2006, 40, 174-183
Synthese definierter (Sekundär-)Strukturen
11. C. P. R. Hackenberger, M. Chen, B. Imperiali,
Bioorg. Med. Chem. 2006, 14, 5043-5048
Expression of N-terminal Cys-Protein Fragments using an Intein Refolding Strategy
10. C. P. R. Hackenberger, C. T. Friel, S. E. Radford, B. Imperiali
J. Am. Chem. Soc. 2005, 127, 12882-12889
Semisynthesis of a Glycosylated Im7 Analogue for Protein Folding Studies
9. C. P. R. Hackenberger, M. K. O'Reilly, B. Imperiali
J. Org. Chem. 2005, 70, 3574-3578
Improving Glycopeptide Synthesis: A Convenient Protocol for the Synthesis of ß-Glycosylamines and the Synthesis of Glycopeptides
8. C. Bolm, M. Verrucci, O. Simic, C. P. R. Hackenberger
Adv. Synth. Catal. 2005, 347, 1696-1700
Ethylene-Bridged Bissulfoximines in Copper-Catalyzed Enantioselective Hetero-Diels-Alder Reactions
7. C. P. R. Hackenberger, G. Raabe, C. Bolm
Chem. Eur. J. 2004, 10, 2942-2952
Synthetic and Spectroscopic Investigation of N-Acylated Sulfoximines
6. C. P. R. Hackenberger, I. Schiffers, J. Runsink, Carsten Bolm,
J. Org. Chem. 2004, 69, 739-743
General Synthesis of Unsymmetrical Norbornane Scaffolds as Inducers for Hydrogen Bond Interactions in Peptides
5. C. Bolm, I. Schiffers, I. Atodiresei, C. P. R. Hackenberger
Tetrahedron: Asymmetry 2003, 14, 3455-3467
The alkaloid-mediated desymmetrization of meso-anhydrides by nucleophilic ring opening with benzyl alcohol and its application in the synthesis of highly enantiomerically enriched ß-amino acids
4. C. Bolm, D. Müller, C. Dalhoff, C. P. R. Hackenberger, E. Weinhold
Bioorg. Med. Chem. Lett. 2003, 13, 3207-3211
The Stability of Pseudopeptides Bearing Sulfoximines as Chiral Backbone Modifying Element towards Proteinase K
3. C. Bolm, C. P. R. Hackenberger, O. Simic, M. Verrucci, D. Müller,
F. Bienewald
Synthesis 2002, 7, 879-887
N-Alkylation of Sulfoximines: A Mild Synthetic Procedure for the Introduction of Carbon Side-Chains via an Acylation and Reduction Route
2. C. Bolm, D. Müller, C. P. R. Hackenberger
Org. Lett. 2002, 4, 893-897
Turn Formation Initiated by a Bissulfoximine Motif: Synthesis and Structural Investigation
1. S. M. Yu, D. T. McQuade, M. A. Quinn, C. P. R. Hackenberger,
M. P. Krebs, A. S. Polans and S. H. Gellman
Protein Sci. 2000, 9, 2518-2527
An Improved Tripod Amphiphile for Membrane Protein Solubilization

Patents

  1. C. P. R. Hackenberger, R. Serwa, G. del Signore
    patent application filed
    Mit einer Phosphoramidatgruppe modifizierte Makromoleküle und deren Verwendung

Academic publications

  1. C. P. R. Hackenberger,
    Masters thesis    , Wisconsin/Madison, 1999
    Thermal Stability of Tripod Amphiphiles: A Kinetic Investigation of the Cope-Elimination of Amine-Oxides Designed to Promote Membrane Protein Crystallization
  2. C. P. R. Hackenberger,
    Dissertation    , RWTH Aachen, 2003
    Untersuchungen zu chemischen und strukturbildenden Eigenschaften von Sulfoximidoylen und Sulfoximin-ß-Carbonylen: Definierte Sekundärstruktur in Pseudopeptiden, Oligomeren und molekularen Gerüstsystemen

Other publications, book reviews, conference reports, scientific journalism

  1. Author within the television broadcast
    Quarks und Co.- The Star of Bethlehem, broadcasted on 12/18/2001 on WDR
  2. Editorial office assistant and author within the WDR-Series
    WissQuiz, broadcasted from 12/26 – 12/30/2001 on WDR
  3. Various publications and reports for the JCF Spring Symposium
    Euregionale 2002 in Aachen
  4. C. Bolm, C. P. R. Hackenberger, J. Rudolph,
    Adv. Materials     2002, 14, 168-169
    Catalysis from A to Z; A Concise Encyclopedia, B. Cornils, W. A. Herrmann, R. Schlögl, C.-H. Wong (eds.) book review
  5. E. C. Ullrich, U. Kallfass, C. P. R. Hackenberger,
    Nachrichten aus der Chemie    , 2002, 50, 1359-1362
    Öffentlichkeitsarbeit für die Chemie
  6. C. P. R. Hackenberger,
    Nachrichten aus der Chemie    , 2004, 1, 29
    Deutsche Hochschulen – Fit für den internationalen Wettbewerb? conference report
  7. C. P. R. Hackenberger,
    Nachrichten aus der Chemie    , 2006, 1, 64
    14. Nachwuchsiwssenschaftlersymposium Bioorganische Chemie conference report
  8. Author "RÖMPP-online"
    Thieme Verlag, ab Oktober 2007
  9. C. P. R. Hackenberger, H. Wegener, A. Zumbuehl
    Angew. Chem.     2008, 120, 5578-5581
    Angew. Chem. Int. Ed. 2008, 47, 5496-5499
    Stereochemie in Bürgenstock: chemische Biologie und organische Synthese im Blickpunkt (Konferenzbericht)

Oral and poster presentations

download pdf-file: Prof. Hackenberger

download pdf-file: Mitarbeiter AG Hackenberger