ENTRY A34378 #type complete TITLE endothelin 3 precursor - human CONTAINS big endothelin 3; endothelin 3; endothelin homolog ORGANISM #formal_name Homo sapiens #common_name man DATE 08-Jun-1990 #sequence_revision 26-May-1994 #text_change 09-Jun-1994 ACCESSIONS A34378; S08262 REFERENCE A34378 #authors Bloch, K.D.; Eddy, R.L.; Shows, T.B.; Quertermous, T. #journal J. Biol. Chem. (1989) 264:18156-18161 #title cDNA cloning and chromosomal assignment of the gene encoding endothelin 3. #cross-references MUID:90036893 #accession A34378 ##molecule_type mRNA ##residues 1-238 ##label BLO ##cross-references GB:J05081 ##note the source of this mRNA was hypothalamus REFERENCE S08262 #authors Onda, H.; Ohkubo, S.; Ogi, K.; Kosaka, T.; Kimura, C.; Matsumoto, H.; Suzuki, N.; Fujino, M. #journal FEBS Lett. (1990) 261:327-330 #title One of the endothelin gene family, endothelin 3 gene, is expressed in the placenta. #cross-references MUID:90184472 #accession S08262 ##molecule_type DNA ##residues 1-180,'RQ',197-238 ##label OND ##note sequence not compared to nucleotide translation ##note the source of this mRNA was placenta GENETICS #gene GDB:EDN3 #map_position 20q13.2-q13.3 CLASSIFICATION #superfamily endothelin KEYWORDS vasoconstriction FEATURE 1-16 #domain signal sequence #status predicted #label SIG\ 97-138 #protein big endothelin 3 #status predicted #label BMAT\ 97-117 #protein endothelin 3 #status predicted #label MAT\ 159-179 #protein endothelin homolog #status predicted #label HOM\ 97-111,99-107, 159-173,161-169 #disulfide_bonds #status predicted SUMMARY #length 238 #molecular-weight 25454 #checksum 2435 SEQUENCE 5 10 15 20 25 30 1 M E P G L W L L F G L T V T S A A G F V P C S Q S G D A G R 31 R G V S Q A P T A A R S E G D C E E T V A G P G E E T V A G 61 P G E G T V A P T A L Q G P S P G S P G Q E Q A A E G A P E 91 H H R S R R C T C F T Y K D K E C V Y Y C H L D I I W I N T 121 P E Q T V P Y G L S N Y R G S F R G K R S A G P L P G N L Q 151 L S H R P H L R C A C V G R Y D K A C L H F C T Q T L D V S 181 S N S R T A E K T D K E E E G K V E V K D Q Q S K Q A L D L 211 H H P K L M P G S G L A L A P S T C P R C L F Q E G A P /// .