Laboratory of
Cell Biochemistry
Selected Publications
Ralf Erdmann, Marten Veenhuis, Daphne Mertens, and Wolf-Hubert Kunau (1989).
Isolation of peroxisome-deficient
mutants of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 86:5419-5423.
Ralf Erdmann, Franziska F. Wiebel, Arne Flessau, Joanna Rytka, Andreas Beyer, Kai-Uwe Fröhlich, and Wolf-Hubert Kunau (1991). PAS1, a yeast gene required for peroxisome biogenesis, encodes a member of a novel family of putative ATPases. Cell 64:499-510.
Ralf Erdmann and Wolf-Hubert Kunau (1992). A genetic approach to the biogenesis of
peroxisomes in the yeast Saccharomyces cerevisiae. Cell Biochem.
Funct. 10:167-174.
Ralf Erdmann (1994). The peroxisomal targeting signal of 3-oxoacyl-CoA thiolase from Saccharomyces cerevisiae. Yeast 10:935-944.
Martina Marzioch, Ralf Erdmann, Marten Veenhuis, and Wolf-Hubert Kunau (1994). PAS7 encodes a novel yeast member of the WD-40 protein family essential for import of 3-oxoacyl-CoA thiolase, a PTS2-containing protein, into peroxisomes. EMBO J. 13:4908-4918.
Thomas Krause, Wolf-Hubert Kunau, and Ralf Erdmann (1994). Effect of site-directed mutagenesis of
conserved lysine residues upon Pas1 protein function in peroxisome biogenesis. Yeast
10:1613-1620.
Ralf Erdmann and Günter
Blobel (1995). Giant peroxisomes in oleic acid-induced Saccharomyces
cerevisiae lacking the peroxisomal membrane protein Pmp27p. J. Cell
Biol. 128:509-523.
Fabian Blobel and Ralf Erdmann (1996). Identification of a yeast peroxisomal member of the AMP-binding protein family. Eur. J. Biochem., 240:468-476.
Ralf Erdmann and Günter Blobel (1996). Identification of Pex13p, a membrane receptor for the PTS1 recognition
factor. J. Cell Biol. 135:111-121.
Ralf Erdmann and Wolf-Hubert Kunau (1997). Protein import into peroxisomes. in: Eukaryotism and Symbiosis, H. E. A. Schenk, R. Herrmann, K. W. Jeon, N. E. Müller, W. Schwemmler (eds.), Springer-Verlag Berlin Heidelberg, S. 195-205.
Markus Albertini, Peter Rehling, Ralf Erdmann, Wolfgang Girzalsky, Jan Kiel,
Marten Veenhuis, and Wolf-Hubert Kunau (1997). Pex14p, a membrane receptor for both PTS1 and
PTS2 dependent protein import. Cell 89:83-92.
Klaudia Götte, Wolfgang Girzalsky,
Evelyn Baumgart, Wolf-Hubert Kunau, and Ralf Erdmann (1998). Pex19p, a
Farnesylated Protein Essential for Peroxisome Biogenesis. Mol. Cell. Biol.
18:616-628.
Ralf Erdmann, Marten Veenhuis, and Wolf-Hubert Kunau. (1997). Peroxisome biogenesis at the
cross-roads. Trends Cell Biol.7: 400-407.
Birgit Henke, Wolfgang
Girzalsky, Veronique-Berteaux-Lecellier, and Ralf Erdmann (1998). IDP3
encodes a peroxisomal NADP-dependent isocitrate dehydrogenase required for the
ß-oxidation of unsaturated fatty acids. J. Biol. Chem. 272:3702-3711.
Wolf-Hubert Kunau and Ralf Erdmann (1998). Peroxisomes: back to the endoplasmatic
reticulum? Current Biology 8, 299-302.
Garnet K. Will, Monika
Soukupova, Xinji Hong, Kai S. Erdmann, Jan A.K.W. Kiel, Gabriele Dodt, Wolf-H. Kunau,
and Ralf Erdmann (1999). Identification
and characterization of the human orthologue of yeast Pex14p. Mol. Cell.
Biol. 19, 2265-2277.
Wolfgang Girzalsky, Peter Rehling, Katharina Stein, Julia Kipper, Lars
Blank, Wolf-H. Kunau, and Ralf Erdmann (1999). Involvement of Pex13p in Pex14p localization and PTS2-dependent protein
import into peroxisomes. J. Cell Biol. 144, 1151-1162.
John M.
Jones, Katja Nau, Michael T. Geraphty, Ralf Erdmann, and Stephen J. Gould
(1999). Identification and functional analysis of Tes1p, a peroxisomal
thioesterase required for degradation of fatty acids. J. Biol. Chem. 274,
9216-9223
Wolfgang Girzalsky, Peter Rehling, Katharina Stein, Julia
Kipper, Lars Blank, Wolf-H. Kunau, and Ralf Erdmann (1999). Involvement of
Pex13p in Pex14p localization and PTS2-dependent protein import into
peroxisomes. J. Cell Biol. 144, 1151-1162
Dirk
Warnecke, Ralf Erdmann, Annette Fahl, Bernhard Hube, Frank Müller, Thorsten Zank, Ulrich Zähringer, and Ernst
Heiny (1999) Cloning and functional expression of UGT genes encoding sterol
glucosyltransferases from Saccharomyces cerevsiae, Candida albicans, Pichia
pastoris, and Dictyostelium discoideum. J. Biol. Chem. 274, 13048-13059
Brian V. Geisbrecht, Kerstin Schulz, Katja Nau, Michael T. Geraghty,
Horst Schulz, Ralf Erdmann, and Stephen J. Gould (1999). Identification characterization of two new yeast
Peroxisomal dienoyl-CoA isomerases. Biochem. Biophys. Res. Com. 260,
28-34
Ewald H. Hettema, Wolfgang
Girzalsky, Marlene van den Berg, Ralf Erdmann and Ben Distel (2000). Saccharomyces
cerevisiae Pex3p and Pex19p are required for proper localization and
stability of peroxisomal membrane proteins.
EMBO J. 19, 223-233.
Peter Rehling, Adriane
Skaletz-Rorowski, Wolfgang Girzalsky, Tineke Voorn-Brouwer, Maartje M. Franse,
Ben Distel, Marten Veenhuis, Wolf-H. Kunau and Rlaf Erdmann (2000). Pex8p, an intraperoxisomal peroxin of S. cerevisiae
required for protein transport into peroxisomes binds the PTS1 receptor
Pex5p. J. Biol. Chem. 275,
3595-3602