ENTRY ISHUT #type complete TITLE triose-phosphate isomerase (EC 5.3.1.1) - human ALTERNATE_NAMES triosephosphate mutase ORGANISM #formal_name Homo sapiens #common_name man DATE 28-Feb-1986 #sequence_revision 28-Feb-1986 #text_change 31-Dec-1993 ACCESSIONS A01164; A23441 REFERENCE A01164 #authors Maquat, L.E.; Chilcote, R.; Ryan, P.M. #journal J. Biol. Chem. (1985) 260:3748-3753 #title Human triosephosphate isomerase cDNA and protein structure. Studies of triosephosphate isomerase deficiency in man. #cross-references MUID:85131186 #accession A01164 ##molecule_type mRNA ##residues 1-248 ##label MAQ REFERENCE A23441 #authors Brown, J.R.; Daar, I.O.; Krug, J.R.; Maquat, L.E. #journal Mol. Cell. Biol. (1985) 5:1694-1706 #title Characterization of the functional gene and several processed pseudogenes in the human triosephosphate isomerase gene family. #cross-references MUID:85267686 #accession A23441 ##molecule_type DNA ##residues 1-248 ##label BRO COMMENT The functional molecule catalyzes the interconversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. It plays an important role in several metabolic pathways. GENETICS #introns 38/1; 79/2; 107/3; 152/1; 180/3; 210/1 CLASSIFICATION #superfamily triose-phosphate isomerase KEYWORDS fatty acid biosynthesis; gluconeogenesis; glycolysis; homodimer; intramolecular oxidoreductase; isomerase; pentose phosphate pathway FEATURE 2-248 #protein triose-phosphate isomerase #label MAT SUMMARY #length 248 #molecular-weight 26538 #checksum 7220 SEQUENCE 5 10 15 20 25 30 1 A P S R K F F V G G N W K M N G R K Q S L G E L I G T L N A 31 A K V P A D T E V V C A P P T A Y I D F A R Q K L D P K I A 61 V A A Q N C Y K V T N G A F T G E I S P G M I K D C G A T W 91 V V L G H S E R R H V F G E S D E L I G Q K V A H A L A E G 121 L G V I A C I G E K L D E R E A G I T E K V V F E Q T K V I 151 A D N V K D W S K V V L A Y E P V W A I G T G K T A T P Q Q 181 A Q E V H E K L R G W L K S N V S D A V A Q S T R I I Y G G 211 S V T G A T C K E L A S Q P D V D G F L V G G A S L K P E F 241 V D I I N A K Q /// .